Tolerance Accumulation

[stew1974]

/o

[Nickaveli]

So does this not mean that you build up a kind of temporary tolerance?

I haven't smoked in about a month so when I pick up this weekend I'm sure it will hit me pretty hard. However if I had been smoking all month, the spliff I have this weekend would leave me chilled rather than laid out?

feeling kinda to be honest lol

[SoulRider]

arrgh i am more confused than ever SR.
i smoke less the more stoned i am = no tolerance.
i drink less the more drunk i am = tolerance.
no smoke for 1 month, smoke joint very stoned. smoke for 1 week smoke similar joint less stoned = no tolerance.
no drink for 1month, drink pint feel effects. drink for 1 week drink similar pint feel no effects = tolerance.
its established i'm an idiot but i don't get it. if you want more effects from a drug use it less, is this not the same for all tolerated and untolerated drugs? i could move the argument on to LSD another drug you say there is no tolerance, again that would be down to receptors but are receptors not a body's tolerance indicator? see i'm going round in circles and back again and more confused.

Let me break it down and try and make it clear from your interpretations:

i smoke less the more stoned i am = no tolerance

: This is correct, if you have reached the level of No more high no matter how much of this shit I smoke, start smoking less, and more receptors will be activated, so you will get more stoned. Ever notice how you never get stoned again like the first time you were stoned?

i drink less the more drunk i am = tolerance

: You got this arse about face, my point is with alcohol, if you drink less, you get less drunk, not more drunk. Less drunk with less intake is tolerance. You need to drink more to get the same amount drunk and is the total opposite of above. This should say - I drink less, the less drunk i am = tolerance.

no smoke for 1 month, smoke joint very stoned. smoke for 1 week smoke similar joint less stoned = no tolerance

: This is the one.....

This one on the face of it seems to indicate tolerance but it doesn't when you understand how MJ works. The first time you have a joint, ever or in ages, you get stoned like nobody's business. Smoke reguarly or too much and you don't get so stoned, so you smoke more. You think this is tolerance, but Receptors are being turned off in your brain so you cannot overdose. The brain says, ok you have been loading me up with THC, and I only have enough bandwidth to accept THC, so I will shut down 'X' number of receptors to inhibit the amount of THC absorbed. You are not tolerant to marijuana. You are not tolerant to THC. You can physically absorb less that is all.

If you understand cars, I will try and use this analogy. Marijuana is going into the brain, like petrol going into the engine. When there is a flow of too much fuel into the engine, the engine will automatically restrict the flow of fuel to prevent overrich burning (this assumes your car has a brain or EMS). Does this mean the engine has become tolerant to fuel? No it has restricted it's intake to avoid overfuelling. The brain is the same. 1 molecule of THC will always have the same effect on your body, no matter how much weed you smoke, it's just the more reguarly or larger the amount you smoke, the more the brain restricts the flow of THC to the brain.

no drink for 1month, drink pint feel effects. drink for 1 week drink similar pint feel no effects = tolerance

: correct

Does this make sense to people now? Do you understand that 'Tolerance' does not exist, all the brain has is a limiter. When THC flow reaches a level, the limiter kicks in and receptors are shut down, when you smoke less, the limiter turns off and you get the effect of all the THC molecules you are smoking at once, rather than a few of them.

I know the people who are looking to 'lower their tolerance' so they can smoke less, but you cannot ever lower your tolerance, because you don't have any with Marijuana. There is a limit in your brain to how high you can get, once you reach that place there is no higher place you can be.

The same can't be said for being 'Stoned'....

Being stoned causes more than just a brain action, being stoned becomes a physical issue, and causes your blood sugar to drop, so that if you don't replenish you can whitey.

Of course, that's not to say that you can't smoke a shit load of THC before you're brain has shut off the receptors, to make yotu really fly, but the more you smoke, the quicker the receptors are shut down. All those people who smoke too much, you do it, because you do it. Realise you just can't get no higher with weed.

[stew1974]

/o

[SoulRider]

You are not infuriating, I know as well as anyone that words are the worst way to try and convey an experience...

The theory of your statement is correct, but the trouble is the amount of THC is going to be different for each person, batches of weed are never the same, Every day THC is breaking down and CBD's are increasing in strength. All weeds have different strength's and cocktails of cannabinoids.

I can't say how much should be smoked, but if you are smoking and not getting any higher, then it's safe to assume you need to smoke less than you are

[stew1974]

/o

[stew1974]

/o

[SoulRider]

It's all cool.

The Cannabinoids produced in Marijuana are the only substances in the universe to have a receptor in the human brain that are not created by the human brain. As much as people like to use Marijuana as a recreational drug, it is, and always will be, a major part of the human biological make-up and therefore is only ever medicinal in it useage. It is because of this that you can never have too much, and can't carry on pushing yourself further and further like you can with almost every other drug in the world.

When you are at your fill of Marijuana, you are at your fill, no matter how much more you smoke.

When people who smoke marijuana realise this, they can then if they choose learn to understand how much they actually need to smoke, and how much they can cut back by. I am currently being amazed at how little I can smoke and still keep myself stoned all day long

I am also amazed at how much more organised and better I am leading my life now I smoke less. A hidden benefit if you like

I still smoke too much, but it's coming down in volume

Also as regards the Volume x Effect X Time X Time argument still holds true. It's just that the volume is reduced, because less i sbeing absorbed by the body. Let me try and explain with a maths formula. I have never done this outside of maths at school, which I left 17 years ago, so let's see what I can remember, and if I get it wrong if people could correct the formula rather than just tell me I'm wrong

A basic equation for first time use of weed and alcohol:

Effect= (Intake=Volume Absorbed) X Time to absorb

I will compare alcohol and Weed when they have been used over time:

Alcohol Effect= ((Intake=Volume Absorbed) X Time to Absorb)/Length of use

Weed Effect= (Intake/length of use=Volume Absorbed) X Time to Absorb

With Alcohol the intake is always equivalent to the volume absorbed. This is multiplied with speed in which you drank the alcohol. You then divide by your length of use, and this gives you the effect of the alcohol on your body. meaning the longer you have used alcohol, the less the equivalent effect on your body.

With Marijuana, the length of use just serves to shut down receptors, this means that the intake divided by the number of receptors that have been shut down (length of use) provides you with the amount the brain can absorb. This is then multiplied by the time taken to absorb. So what happens here is the longer you smoke, the less you can absorb, but the effect is still 100% of that which you absorbed and not weakened by the length of use like Alcohol.

That may not work but it appears to make at least a bit of sense to me

[TwoCanucks]

i smoke less the more stoned i am = no tolerance

: This is correct, if you have reached the level of No more high no matter how much of this shit I smoke, start smoking less, and more receptors will be activated, so you will get more stoned. Ever notice how you never get stoned again like the first time you were stoned?

What happens is the receptors which have been activated by 1gram joints (for example) are looking for the same stimuli when you smoke a 0.2gram joint.

In order for those rececptors to find that THC, more of them activate in search of THC.

[chilly1952]

Andy, if I had a debating team I would want you on it.

There are parts of your stance that I agree with. Yes, that small amount of smoke will always give a buzz. The degree of that buzz is where I feel there is a difference from tolerance. I also agree that there is a ceiling or wall that is reached where you get no higher, thank God. I’m not sure if it’s a shut down of receptors or an over saturation to the point where there are insufficient receptors available to achieve a higher level of stimulation. It’s the buzz in between these two ends of the spectrum is where I disagree. May I reference one of your recent post about a mate of yours coming over and smoking, I think it was Algerian, weed from Centraal CS and getting a white out? Why didn’t the same thing happen to you?

We are very complex mechanisms as is the cannabis plant itself. Could it be that the all the effects sited in this string are occurring at the same time? Kind of like Forest Gump’s revelation that fate and freewill both exist together in life. Could the body be adjusting to the stimulus at either a physical or mental level giving us an increased tolerance at the same time allowing us to get a buzz off a few tokes and still not allow us to OD from one of our 420 like smoking session? Another words, is everyone right here?

[Pauli Wallnuts]

Andy, if I had a debating team I would want you on it.

There are parts of your stance that I agree with. Yes, that small amount of smoke will always give a buzz. The degree of that buzz is where I feel there is a difference from tolerance. I also agree that there is a ceiling or wall that is reached where you get no higher, thank God. I’m not sure if it’s a shut down of receptors or an over saturation to the point where there are insufficient receptors available to achieve a higher level of stimulation. It’s the buzz in between these two ends of the spectrum is where I disagree. May I reference one of your recent post about a mate of yours coming over and smoking, I think it was Algerian, weed from Centraal CS and getting a white out? Why didn’t the same thing happen to you?

We are very complex mechanisms as is the cannabis plant itself. Could it be that the all the effects sited in this string are occurring at the same time? Kind of like Forest Gump’s revelation that fate and freewill both exist together in life. Could the body be adjusting to the stimulus at either a physical or mental level giving us an increased tolerance at the same time allowing us to get a buzz off a few tokes and still not allow us to OD from one of our 420 like smoking session? Another words, is everyone right here?

you definatly would want him on your team, he convinced a whole table at a 420 meet that heroin&crack should not only be legal but given 2 whoever wants it 4free, & that if u did smoke crack it was your purpose in life, i know it sounds crazy but when you actually put what he said together & think about it, it actually makes sense, BTW hows it going Andy still enjoying your 200euro a month view

[SoulRider]

It’s the buzz in between these two ends of the spectrum is where I disagree. May I reference one of your recent post about a mate of yours coming over and smoking, I think it was Algerian, weed from Centraal CS and getting a white out? Why didn’t the same thing happen to you?

Because I'm not an idiot and I put much less weed in than him.

Whitey's are not what we are talking about. Whitey's are because your blood sugar level drops. They are totally seperate to the discussion of the THC effect on your brain. This has nothing to do with it. Marijuana causes your blood sugar to drop. If you do not take in more sugar, you get a whitey. This is why you are given sugar water when you have a whitey. You can have a whitey by smoking a 0.1g spliff at lunchtime having not eaten and then going for a walk Even if you smoked 20g the night before.

There are many different components to Marijuana, and that is why you have to look at the plant holisticly rather than individually. I explain how certain compnents work on the body, but if you don't understand how the other bits work, there appear to be contradictions. Trust me, there is a lot of contradictions with Marijuana. It is both stimulant and depressant for example. I have done a shit load of research into Marijuana, and while I try to explain my views, if you guys have an interest, why don't you investigate the issue for yourselves? That way I'd have people to talk about Marijuana with, rather than explaining it

Oh and I'd be no good on a debating team, it takes me about 5 attempts before I get the explanation clear enough for people, more than enough time to give ammunition to people to tear me apart )

[SoulRider]

you definatly would want him on your team, he convinced a whole table at a 420 meet that heroin&crack should not only be legal but given 2 whoever wants it 4free, & that if u did smoke crack it was your purpose in life, i know it sounds crazy but when you actually put what he said together & think about it, it actually makes sense, BTW hows it going Andy still enjoying your 200euro a month view

I hope I didn't convince people, I hope they listened to my view point, considered it for themselves, and then made up their own minds

[DC]

"I reject your reality and substitute my own"

[hestia]

question, do you get a whitie because of the amount of thc you injest or because you haven't been eating? This leads me to another question, are you just so high you forget to eat or dose the smoke retard your hunger responces?