As usual, the main purpose will be to visit Dutch relatives but we love sightseeing there too and I generally manage to slip off to a coffeeshop or two
I used Priceline to book accommodation and got the 4* Moevenpick Amsterdam City Center hotel for £55 per night (£61 including taxes). This is way less than the rack rate and significantly less than we paid last week or could get in October for a really basic (but clean and fantastically located) place with no en suite bathroom. I think the Moevenpick will be an interesting location - right behind the Centraal Station, fab views over the water and city, right by a tramstop, and next to the Stedelik, Nemo and Scheepsvart museums and the new MusiekGebouw.
But anyone from this board bidding 4* city centre / museum district on Priceline should be aware that the Moevenpick is a non-smoking hotel (eek - no late night pre-rolls for me) and that it is a 10-15 minute walk to where the action starts if you don't want to rely on trams.